SF
San Francisco 49ers
Schedule
Complete 2025-2026 season schedule and results
Record: 13-6 (0.684)
Week 1
Sun, Sep 7 FOX
SF
San Francisco 49ers 17
FINAL W
SEA
Seattle Seahawks 13
Lumen Field
Week 2
Sun, Sep 14 FOX
SF
San Francisco 49ers 26
FINAL W
NO
New Orleans Saints 21
Caesars Superdome
Week 3
Sun, Sep 21 FOX
ARI
Arizona Cardinals 15
FINAL W
SF
San Francisco 49ers 16
Levi's Stadium
Week 4
Sun, Sep 28 FOX
JAX
Jacksonville Jaguars 26
FINAL L
SF
San Francisco 49ers 21
Levi's Stadium, Santa Clara, CA
Week 5
Thu, Oct 2 Prime Video
SF
San Francisco 49ers 26
FINAL W
LAR
Los Angeles Rams 23
SoFi Stadium
Week 6
Sun, Oct 12 CBS
SF
San Francisco 49ers 19
FINAL L
TB
Tampa Bay Buccaneers 30
Raymond James Stadium
Week 7
Sun, Oct 19 NBC
ATL
Atlanta Falcons 10
FINAL W
SF
San Francisco 49ers 20
Levi's Stadium
Week 8
Sun, Oct 26 FOX
SF
San Francisco 49ers 15
FINAL L
HOU
Houston Texans 26
NRG Stadium
Week 9
Sun, Nov 2 CBS
SF
San Francisco 49ers 34
FINAL W
NYG
New York Giants 24
MetLife Stadium
Week 10
Sun, Nov 9 FOX
LAR
Los Angeles Rams 42
FINAL L
SF
San Francisco 49ers 26
Santa Clara, CA
Week 11
Sun, Nov 16 FOX
SF
San Francisco 49ers 41
FINAL W
ARI
Arizona Cardinals 22
State Farm Stadium
Week 12
Mon, Nov 24 ESPN
CAR
Carolina Panthers 9
FINAL W
SF
San Francisco 49ers 20
Levi's Stadium
Week 13
Sun, Nov 30 CBS
SF
San Francisco 49ers 26
FINAL W
CLE
Cleveland Browns 8
Cleveland Browns Stadium
Week 15
Sun, Dec 14 CBS
TEN
Tennessee Titans 24
FINAL W
SF
San Francisco 49ers 37
Levi's Stadium
Week 16
Mon, Dec 22 ESPN/ABC
SF
San Francisco 49ers 48
FINAL W
IND
Indianapolis Colts 27
Lucas Oil Stadium
Week 17
Sun, Dec 28 NBC
CHI
Chicago Bears 38
FINAL W
SF
San Francisco 49ers 42
Levi's Stadium
Week 18
Sat, Jan 3 ESPN/ABC
SEA
Seattle Seahawks 13
FINAL L
SF
San Francisco 49ers 3
Levi's Stadium
Wild Card
Sun, Jan 11 NBC
SF
San Francisco 49ers 23
FINAL W
PHI
Philadelphia Eagles 19
Lincoln Financial Field
Divisional Round
Sun, Jan 18 FOX
SF
San Francisco 49ers 17
FINAL L
SEA
Seattle Seahawks 42
Lumen Field