The final injury report of the Philadelphia Eagles' 2025 season tells a story of a team that was physically compromised at the most critical moment. Several key starters were either sidelined or limited in the season-ending 23-19 Wild Card loss to the San Francisco 49ers, directly impacting the game's outcome.
The most significant absence was perennial All-Pro right tackle Lane Johnson. The veteran anchor of the offensive line was officially listed as questionable all week with a foot injury and was ultimately declared inactive for the game. His replacement, Jack Driscoll, struggled at times against the 49ers' formidable pass rush, disrupting the timing of the Eagles' offense and contributing to the pressure on Jalen Hurts.
The offensive line took another hit when backup center Brett Toth was downgraded from questionable to out due to a concussion suffered in practice. This further eroded the depth and stability of a unit that prides itself on being a team strength.
On defense, linebacker Azeez Ojulari, a key rotational pass rusher, was listed as questionable with a hamstring injury. While he was active, it is likely he was not at 100%, limiting his effectiveness in a game where generating pressure was paramount.
These playoff ailments were the culmination of a late-season injury wave. In the Week 18 loss to Washington, the Eagles were already without defensive tackle Jalen Carter (hip), tight end Dallas Goedert (knee), and linebacker Nakobe Dean (hamstring). While some, like Goedert, returned for the playoffs, they may not have been operating at peak capacity.
The collective toll of these injuries, particularly on the offensive line, proved too much to overcome against a talented 49ers squad. As the Eagles enter the offseason, ensuring the health and durability of their core players—and building more reliable depth behind them—will be a major point of emphasis for the training and personnel staffs. The 2026 schedule, which features eight 2025 playoff teams, offers no respite, making durability as valuable as talent.